News
July 11, 2025

Understanding Genetic Testing: Assessing Your Alzheimer's Risk

If someone in your family has been diagnosed with Alzheimer’s disease, you may wonder what does this mean for me? While family history can raise your risk, it doesn’t guarantee you’ll develop the disease. That’s where genetic testing comes in.

Genetic tests can provide insight into your personal risk profile, especially if you’re concerned about early symptoms or planning ahead for your health. But it’s important to understand what these tests can and cannot tell you.

What Genes Are Linked to Alzheimer’s?

There are two main categories of genetic influence:

  1. Early-Onset Genes (rare, but high impact):
    Mutations in APP, PSEN1, and PSEN2 can directly cause early-onset Alzheimer’s, usually before age 65. These mutations are inherited in an autosomal dominant pattern and are responsible for only a small percentage of cases.
  2. Late-Onset Risk Genes (more common):
    The APOE gene, particularly the APOE-e4 variant, is the most well-studied risk gene for Alzheimer’s. Having one copy of APOE-e4 increases your risk; two copies raise it further. However, many people with APOE-e4 never develop Alzheimer’s, and others without it still do.

Should You Get Tested?

Genetic testing is a personal choice. It may be useful if you:

  • Have a strong family history of early-onset Alzheimer’s
  • Are experiencing symptoms at a younger age
  • Are considering joining a clinical trial
  • Want to make long-term life or care decisions with more clarity

Before testing, it’s recommended to speak with a genetic counselor or physician to understand the implications and emotional impact of the results.

Limitations to Keep in Mind

  • Genetic tests can reveal risk, not certainty
  • Results may cause anxiety or impact insurance coverage
  • Knowing your status doesn’t change current treatment options but it may influence prevention strategies

Next Steps for Brain Health Monitoring

Regardless of genetic risk, routine cognitive screening is one of the most effective tools for early detection. You can start today with a free, science-based memory check at:
👉 https://braincheck.discerntest.com

Final Thoughts

Genetic testing can offer clarity but it’s just one piece of the Alzheimer’s puzzle. Understanding your risk is valuable, but so is staying proactive with lifestyle choices, brain health tracking, and early screening.